The male suspect reportedly stole the vehicle from the town hall of Nanterre and hit pedestrians on the forecourt of La Défense. One person has been killed in the horror attack, while another was injured. The suspect fled on foot but was later arrested by the police.
The vehicle used is understood to be a street cleaning vehicle.
The shocking attack took place near the Grande Arche de la Défense.
Local police have said they do not believe the incident is terror related.
It is not yet known why the suspect, who prosecutors claim is a homeless man, decided to plough into the pedestrians.
An investigation has been launched by the judicial police.
According to an eye witness, dozens of police and firefighters quickly arrived at the scene.
Emergency personnel are understood to have tried to resuscitate one of the victims.
Forensic officers remain at the scene.
France has seen a spate of terror attacks in recent years, prompting the Government to raise its terrorism alert to the highest level last October.
The move came after three people were killed and several others wounded in a knife attack in Nice.
Just days before, a school teacher was killed and beheaded outside the school where he worked in Conflans-Sainte-Honorine, a town north west of Paris.
The teacher was killed for showing pupils a cartoon of the Prophet Muhammad.
More to follow…